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Spine Anatomy & Glossary A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z OP-1 - osteogenic protein 1. This bone morphogenetic protein causes bone formation and fusion. osteoporosis - Decreased bone density which occurs frequently in elderly females. osteoarthritis - A normal aging process where spurs develop in the spine. The discs lose water content and become narrowed. osteomyelitis - An infection of bone.